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  Collaborators Funding
PET4PETs
We will build a new generation of multi-tracer PET to improve staging and allow screening for personalized target based cancer therapy in dogs and humans affected by sarcoma.
Institut für Teilchenphysik ETH / Radiopharmazie des Paul Scherrer Institut Kantonsspital Baden /Universitätsspital Zürich / Kantonsspital Baden SNF
2025-2029
Personalizing hypo- and ultra-hypofractionated radiotherapy  
We leverage spontaneous canine tumors to develop an RNAseq-derived fraction-dynamic radiosentitivity signature
Medizinphysik (Radiotherapie Hirslanden, Physik UZH) / Applied Complex Systems Scientists der ZHAW SNF
2025-2029
Deciphering the STS-landscape
We combine spatially defined transcriptomics with clinical outcome data to improve diagnosis and therapy of canine soft-tissue sarcoma
  American Kennel Club

FEATHER-trial (phase II/III randomized trial)
We assess toxicity and efficacy of ultra-high dose rate (FLASH) vs. conventional dose rate proton therapy in feline oral squamous cell carcinoma to model human H&N tumors

 

Paul Scherrer Institut / Oncology Department, HUG Swiss Cancer Research
2023-2026

vISION-S (Phase III randomized trial)
We make naturally occurring sacromas in dogs visible during surgery using two different dyes. The aim ist o determine which one can help best to improve precision of resection.
10.17590/asr.0000321

Institute for Veterinary Pathology Vetsuisse Zürich (Frauke und Paula verlinken), MEEI Institute Harvard University

SNF 2025-2028

Gesellschaft für Kynologische Forschung (2023-2026)
DECODE-AS (ex-vivo)
We sequence hemangiosarcoma to detect new diagnostic and therapeutic targets.
Institute for Veterinary Pathology Vetsuisse Zürich Morris Foundation D24CA-044 (2024-2026)
Charakterisierung von Tumor spezifischen Proteinsignaturen zur Ziel-gerichteten Tumortherapie beim soliden und disseminierten Histiozytären Sarkom.
We sequence histiocytic sarcoma to detect new diagnostic and therapeutic targets.
 
Institute for Veterinary Pathology Vetsuisse Zürich Albert-Heim Stiftung (2023-2026), American Kennel Club (2024-2027)

Vergleichende Untersuchung von Indocyanin Grün und AngiostampTM zur Verbesserung der chirurgischen Therapie bei Hunden mit peripheren Nervenscheidentumoren des Plexus Brachialis oder Lumbalis.
We make naturally occurring sacromas of the great nerves (plexustumors)  in dogs visible during surgery using two different dyes. The aim ist o determine which one can help best to improve precision of resection.

10.17590/asr.0000320

Institute for Veterinary Pathology Vetsuisse Zürich Gesellschaft zur Förderung kynologischer Forschung
STS across species
We leverage similarity in STS between humans and dogs to identify novel treatments for patients of both species.
Charité Berlin, Institute for Veterinary Pathology Vetsuisse Zürich SNF 2025-2028
USTS in dogs
We identify novel tumor-specific targets in canine undifferentiated soft-tissue sarcomas for novel therapies.
Institute for Veterinary Pathology Vetsuisse Zürich Gesellschaft zur Förderung kynologischer Forschung
Decipher-STS dog
We study the single-cell landscape of soft-tissue sarcomas in dogs to identify novel therapy targets.
  Morris Animal Foundation (D24CA-046)
Decipher-STS cat
We study the single-cell landscape of soft-tissue sarcomas in cats to identify novel therapy targets.
  EveryCat Health Foundation